Neue 17-(3-Imino-2-alkyl-propenyl)-5beta-14beta-Androstanderivate, zur Behandlung von kardiovaskulären Erkrankungen, ein Verfahren zu ihrer Herstellung und pharmazeutische Präparate davon

The invention relates to 17-(3-Imino-2-alkylpropenyl)-14 beta -hydroxy-5 beta -androstane derivatives of general formula (I): wherein: the symbol @ means alpha or beta configuration; the double bonds are in the E configuration; and wherein R -R have the meanings defined in the description, as well a...

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Hauptverfasser: BIANCHI, GIUSEPPE, I-20133 MILAN, IT, FERRARI, PATRIZIA, I-21100 VARESE, IT, QUADRI, MARIA L., I-20063 CERNUSCO S/N (MILAN), IT, MELLONI, PIERO, I-20091 BRESSO (MILAN), IT, CERRI, ALBERTO, I-20060 GESSATE (MILAN), IT
Format: Patent
Sprache:ger
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Zusammenfassung:The invention relates to 17-(3-Imino-2-alkylpropenyl)-14 beta -hydroxy-5 beta -androstane derivatives of general formula (I): wherein: the symbol @ means alpha or beta configuration; the double bonds are in the E configuration; and wherein R -R have the meanings defined in the description, as well as to a process for their manufacture and to pharmaceutical compositions comprising the same. These compounds are useful for the treatment of cardiovascular disorders.