Antimigräne Zyklobutendion-Derivate von Tryptaminen

Substd. cyclobutene dione cpds. of formula (I) and their acid addition salts and/or solvates are new. R1 is H, halogen or 1-4C alkyl; R2 and R3 are H or 1-4C alkyl; R4 is H, 1-4C alkyl, 1-4C acyl or 1-4C alkylsulphonyl; X is -NR2R3, -OR2 or R6 where R6 is H, 1-4C alkyl, cycloalkyl, phenyl or phenyl-...

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Hauptverfasser: SOLOMON, CAROLA, COTE ST. LUC, QUEBEC H4W ZV5, CA, GYLYS JONAS A ., GYLYS JONAS A ., SOUTHINGTON, CONNECTICUT 06489, US, RUEDIGER EDWARD H., RUEDIGER EDWARD H., GREENFIELD PARK, QUEBEC J4V2K3, CA, YEVICH, JOSEPH P., SOUTHINGTON, CONNECTICUT 06489, US, SMITH, DAVID W., MADISON, CONNECTICUT 06443, US
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Zusammenfassung:Substd. cyclobutene dione cpds. of formula (I) and their acid addition salts and/or solvates are new. R1 is H, halogen or 1-4C alkyl; R2 and R3 are H or 1-4C alkyl; R4 is H, 1-4C alkyl, 1-4C acyl or 1-4C alkylsulphonyl; X is -NR2R3, -OR2 or R6 where R6 is H, 1-4C alkyl, cycloalkyl, phenyl or phenyl-(1-4C)alkyl); m is 0-3 (esp. 0); n is 1-5(esp. 2).