NICKELFREIER HÄMOGLOBIN UND VERFAHREN ZU SEINER HERSTELLUNG

According to the present invention removal of nickel from a nickel-containing hemoglobin solution is accomplished by exposing the nickel-containing hemoglobin solution to a chelating agent, preferably a multidentate acetic acid based chelator such as EDTA. Methods are provided that allow obtaining e...

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Bibliographische Detailangaben
Hauptverfasser:	BELVAL, THOMAS K., BROOMFIELD, CO 80020, US, CHIVERS, MARK L., ARVADA, CO 80003, US
Format:	Patent
Sprache:	ger
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES USING MICROORGANISMS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	According to the present invention removal of nickel from a nickel-containing hemoglobin solution is accomplished by exposing the nickel-containing hemoglobin solution to a chelating agent, preferably a multidentate acetic acid based chelator such as EDTA. Methods are provided that allow obtaining essentially nickel-free hemoglobin from nickel-containing hemoglobin solutions, particularly hemoglobin solutions that result from large scale fermentation and/or purification.