GEGEN VIREN WIRKSAME NAPHTOCHINON-VERBINDUNGEN, ZUSAMMENSETZUNGEN UND DEREN VERWENDUNGEN

The present invention provides novel antiviral naphthoquinone compounds, which may be isolated from plants of the genus Conospermum or synthesized chemically, in accordance with the present inventive methods. The antiviral naphthoquionone compounds, derivatives thereof, and prodrugs thereof, may be...

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Bibliographische Detailangaben
Hauptverfasser:	GUSTAFSON, KIRK, R., MT. AIRY, MD 21771, US, PANNEL, LEWIS, SILVER SPRING, MD 20802, US, DECOSTERD, LAURENT, A., CH-1260 NYON, CH, PARSONS, IAN, ITHACA, NY 14850, US, BOYD, MICHAEL, R., IJAMSVILLE, MD 21754, US, CRAGG, GORDON, M., BETHESDA, MD 20814, US, MCMAHON, JAMES, B., FREDERICK, MD 21701, US, CARDELLINA, JOHN, H., II, WALKERSVILLE, MD 21793, US
Format:	Patent
Sprache:	ger
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention provides novel antiviral naphthoquinone compounds, which may be isolated from plants of the genus Conospermum or synthesized chemically, in accordance with the present inventive methods. The antiviral naphthoquionone compounds, derivatives thereof, and prodrugs thereof, may be used alone or in combination with other antiviral agents in compositions, such as pharmaceutical compositions, to inhibit the growth or replication of a virus, such as a retrovirus, in particular a human immunodeficiency virus, specifically HIV-1 or HIV-2, in the treatment or prevention of viral infection.