Automatisches Probeneingabemodul

Methods and apparatus (100) for handling a plurality of sample containers (10) to be processed by an instrument (200) are disclosed. In a preferred embodiment, a retaining means (102) holds the sample containers (10) and is indexed to align one of the sample containers (10) to a position where communication with a sample input port (210) of the instrument (200) is established. A stripper (114) moves a sample container (10) into engagement with the sample port (210) and, most preferably, also urges the sample container (10) into sealing engagement with the sample port (210). An interference fit created between the stripper (114) an the sample container (10) provides a positive force that permits the sample container (10) to be withdrawn and returned to its initial position. A lower arm assembly (120) is disclosed which acts as a stop relative to the sample container (10) and thus, as the stripper (114) continues to move while the sample container (10) is being withdrawn it overcomes the force of the interference fit and disengages the stripper (114). The present invention permits a single sample container (10) to be inserted into a thermal zone (109) to reduce the effects of the thermal zone (109) upon samples not being processed. Methods and apparatus (130,132) for initializing the retaining means (102) are also disclosed that preferably use a relative encoder to establish an initial location. The present invention is also useful for manipulating a plurality of columns such as capillary columns or columns packed with a sorbent.