ELEKTROSPRÜHVORRICHTUNG ZUR ERZEUGUNG EINHEITLICHER SUBMIKROMETER TRÖPFCHEN

An electrospray nebulizer generates an aerosol comprised of submicrometer droplets substantially uniform in size. A liquid sample is supplied at a controlled rate to a capillary needle of the nebulizer, and droplets are formed due to an electrical field in the region about the needle discharge. The...

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Bibliographische Detailangaben
Hauptverfasser: ZARRIN, FAHIMEH, KAUFMAN, STANLEY, DORMAN, FRANK
Format: Patent
Sprache:ger
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Zusammenfassung:An electrospray nebulizer generates an aerosol comprised of submicrometer droplets substantially uniform in size. A liquid sample is supplied at a controlled rate to a capillary needle of the nebulizer, and droplets are formed due to an electrical field in the region about the needle discharge. The tendency of the droplets to disintegrate due to Coulomb forces is counteracted by sources of ionizing radiation within the nebulizer. The ions reduce the charge in each droplet while solvent evaporation reduces the diameter of the droplet. To further ensure against Coulomb disintegration, a controlled air sheath is introduced to the nebulizer for transporting droplets more rapidly downstream. Optionally, solvent vapor can be introduced into the air flow to reduce the rate of solvent evaporation within the nebulizer, and ions can be added to the air flow upstream of the needle discharge.