VERWENDUNG VON 2-(2-NITRO-4-TRIFLUORMETHYLBENZOYL)-1,3-CYCLOHEXANDION ZUR BEHANDLUNG VON TYROSINÄMIE SOWIE PHARMAZEUTISCHE ZUSAMMENSETZUNGEN

The invention concerns novel pharmaceutical compositions containing as an active ingredient a 2-benzoyl-1,3-cyclohexanedione which is an inhibitor of the enzyme 4-hydroxyphenylpyruvate dioxygenase (HPPD). The compositions are valuable in the treating those disorders and diseases in which it is desir...

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Hauptverfasser: MARKSTEDT, MAJ ELISABETH HOLME, S-427 00 BILLDAL, SE, ELLIS, MARTIN KEITH, MACCLESFIELD, CHESHIRE SK10 3QN, GB, LINDSTEDT, SVEN TORVALD, S-222 29 LUND, SE, LOCK, EDWARD ALAN, WILMSLOW, CHESHIRE SK9 5HD, GB, MUTTER, LINDA CAROL, BLOOMFIELD, CA 94952, US, PRISBYLLA, MICHAEL PAUL, RICHMOND, CA 94803, US
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Sprache:ger
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Zusammenfassung:The invention concerns novel pharmaceutical compositions containing as an active ingredient a 2-benzoyl-1,3-cyclohexanedione which is an inhibitor of the enzyme 4-hydroxyphenylpyruvate dioxygenase (HPPD). The compositions are valuable in the treating those disorders and diseases in which it is desirable to intervene in the metabolic sequences catalysed by HPPD, such as in treating tyrosinemia type I.