HYPERTONE ISOCHLORÄMISCHE FORMULIERUNG ZUR BEHANDLUNG DES KREISLAUFSCHOCKS

The present invention relates to hypertonic crystalloid resuscitation fluids particularly useful in treating hemorrhagic shock. A pharmaceutical formulation prepared and selected ratios of sodium chloride and sodium acetate with a total osmolar concentration exceeding 500 mOsm can be used as a small...

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Hauptverfasser: ROCHA-E-SILVA, MAURICIO RUA BATATAIO 558 APTO 14, 01423-SAO PAULO, SP, BR, VELASCO, IRINEU T. RUA BORGES DE BARROS, 05441-SAO PAULO, SP, BR, KRAMER, GEORGE C., GALVESTON, TX 77554, US
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Sprache:ger
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Zusammenfassung:The present invention relates to hypertonic crystalloid resuscitation fluids particularly useful in treating hemorrhagic shock. A pharmaceutical formulation prepared and selected ratios of sodium chloride and sodium acetate with a total osmolar concentration exceeding 500 mOsm can be used as a small volume resuscitation fluid which has little effect on plasma chloride levels. Arterial pressure is improved to the point of sustaining oxygen supply to tissues and organs with a significant increase in oxygen delivery and consumption.