NEUE 19-NOR STEROIDE, DIE AN DER 11-BETA STELLE AN EINE THIOKOHLENSTOFFGRUPPE GEBUNDEN SIND, EIN VERFAHREN ZU IHRER HERSTELLUNG UND ZWISCHENPRODUKTE DAZU

Compounds of formula (I), wherein R17 and R'17 are such that: either R17 and R'17 together form ketone, hydrazono, oxime or methylene, or R17 is hydroxyl, hydroxymethyl or acyloxy and R'17 is hydrogen, alkyl or optionally substitued alkenyl or alkynyl; R3 is hydrogen or alkyl; R16 is...

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Hauptverfasser: VAN DE VELDE, PATRICK, 75019 PARIS, FR, CLAUSSNER, ANDRE, 93250 VILLEMOMBLE, FR, TEUTSCH, JEAN-GEORGES, 93500 PANTIN, FR, NIQUE, FRANCOIS, 94170 LE PERREUX, FR
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Sprache:ger
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Zusammenfassung:Compounds of formula (I), wherein R17 and R'17 are such that: either R17 and R'17 together form ketone, hydrazono, oxime or methylene, or R17 is hydroxyl, hydroxymethyl or acyloxy and R'17 is hydrogen, alkyl or optionally substitued alkenyl or alkynyl; R3 is hydrogen or alkyl; R16 is hydrogen, halogen or alkyl; m is 0, 1 or 2; X, Y and Z are such that: X is methylene, arylene or arylenoxy bonded to the steroid by a carbon atom; Y is a saturated or unsaturated straight or branched aliphatic chain which is optionally interrupted by oxygen; and Z is aryl, arylalkyl or straight or branched alkyl; addition salts thereof, a preparation method therefor, medicinal uses thereof, compositions containing said compounds, and resulting novel intermediates.