VERWENDUNG EINES MBP PEPTIDES ZUR HERSTELLUNG EINES MEDIKAMENTES FÜR DIE BEHANDLUNG VON MULTIPLER SCLEROSE

This invention is directed to therapeutic agents comprising peptides in turn comprising a portion of the T-cell manifested in multiple sclerosis. Embodiments of the invention include peptides, vaccines, receptors and entire (attenuated) T-cells. This invention is also directed to methods using the f...

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Bibliographische Detailangaben
Hauptverfasser:	WEINER, L, HAFLER, ALLEN, WUCHERPFENNING, W
Format:	Patent
Sprache:	ger
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES OF PREPARING SUCH COMPOSITIONS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	This invention is directed to therapeutic agents comprising peptides in turn comprising a portion of the T-cell manifested in multiple sclerosis. Embodiments of the invention include peptides, vaccines, receptors and entire (attenuated) T-cells. This invention is also directed to methods using the foregoing agents to suppress immune response against myelin basic protein, and/or to suppress T-cells that recognize an immunodominant epitope of human myelin basic protein. Additionally, this invention is directed to diagnostic methods and kits for diagnosing multiple sclerosis.