Verfahren zur Herstellung von Zellprotein mit Anti-HIV-Wirkung

A process for obtaining cellular protein having potent anti-HIV activity comprises culturing CD4-positive T cells or myeloid cells in a tissue culture medium under conditions in which the cells are induced to produce and secrete a protein having anti-HIV activity, separating the cells from the cultu...

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Bibliographische Detailangaben
Hauptverfasser: NONOYAMA, MEIHAN, ST.PETERSBURG, FLORIDA 33710, US, LAI, PARTRICK K., CLEARWATER, FLORIDA 34619, US, TANAKA, AKIKO, CLEARWATER, FLORIDA 34622, US
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Sprache:ger
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Zusammenfassung:A process for obtaining cellular protein having potent anti-HIV activity comprises culturing CD4-positive T cells or myeloid cells in a tissue culture medium under conditions in which the cells are induced to produce and secrete a protein having anti-HIV activity, separating the cells from the culture medium containing the protein and then recovering the protein from the medium, wherein the molecular weight of the protein having anti-HIV activity, as measured by gel filtration analysis, is within the range of about 7,000 to about 12,000 daltons.