Pharmazeutische Zubereitung mit kontrollierter Freigabe

A controlled release pharmaceutical preparation comprising a core containing a medicinal compound and a coating layer containing a water-repellent salt and a water-insoluble and slightly water-permeable acrylic polymer having trimethylammoniumethyl group. Said preparation releases a medicinal compou...

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Bibliographische Detailangaben
Hauptverfasser: KOBAYASHI, MASAO, KYOTO-SHI, KYOTO-FU, JP, ISHIKAWA, SHIGEYUKI, MINO-SHI, OSAKA-FU, JP, NODA, KAZUO, TAKARAZUKA-SHI, HYOGO-KEN, JP, OSAWA, TAKASHI, TOYONAKA-SHI, OSAKA-FU, JP
Format: Patent
Sprache:ger
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Beschreibung
Zusammenfassung:A controlled release pharmaceutical preparation comprising a core containing a medicinal compound and a coating layer containing a water-repellent salt and a water-insoluble and slightly water-permeable acrylic polymer having trimethylammoniumethyl group. Said preparation releases a medicinal compound in a sigmoid type dissolution pattern irrespective of the PH of a dissolution medium.