9-SUBSTITUIERTE-8-UNSUBSTITUIERTE-9-DEAZAGUANINE

The specification discloses the compounds of formula I (I) wherein (a) -CH2Ar represents in which R1 represents hydrogen, halogen, C1-C3-alkyl, C1-C3-alkoxy, benzyloxy, hydroxy or trifluoromethyl; and R2 represents hydrogen, halogen, C1-C3-alkyl, C1-C3-alkoxy, benzyloxy, hydroxy or trifluoromethyl;...

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Bibliographische Detailangaben
Hauptverfasser:	EALICK, STEVEN, E., BIRMINGHAM, AL 35205, US, ERION, MARK, DAVID, SAN DIEGO, CA 92121-1207, US, MONTGOMERY, JOHN, A., BIRMINGHAM, AL 35223, US, SECRIST, JOHN, A., III, BIRMINGHAM, AL 35243, US
Format:	Patent
Sprache:	ger
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The specification discloses the compounds of formula I (I) wherein (a) -CH2Ar represents in which R1 represents hydrogen, halogen, C1-C3-alkyl, C1-C3-alkoxy, benzyloxy, hydroxy or trifluoromethyl; and R2 represents hydrogen, halogen, C1-C3-alkyl, C1-C3-alkoxy, benzyloxy, hydroxy or trifluoromethyl; provided that R2 represents hydrogen or C1-C3-alkyl if R1 represents trifluoromethyl, or that R1 represents hydrogen or C1-C3-alkyl if R2 represents trifluoromethyl; or (b) -CH2Ar represents in which X represents sulfur or oxygen and in which attachment to the thiophene or furan ring is at the 2- or 3-position; and tautomers thereof; as purine nucleoside phosphorylase inhibitors.