Derivate von N,N,N',N'-substituiertem 6-(1-Piperazinyl)-2,5-pyridin-diamin, Verfahren zu deren Herstellung und ihre Verwendung als Arzneimittel und pharmazeutische Präparate davon

The invention relates to the compounds (I): in which: - RA and RA', RB and RB' represent hydrogen or alkyl (C1-4) or form a 5- or 6-membered heterocycle optionally substituted with an alkyl (C1-3), Y represents hydrogen or steroid in which: - R6 represents hydrogen, methyl, fluorine or chl...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: LECLAIRE, JACQUES, F-91300 MASSY, FR, NEDELEC, LUCIEN, F-93340 LE RAINCY, FR, PHILIBERT, DANIEL, F-94210 LA VARENNE SAINT HILAIRE, FR, CLAUSSNER, ANDRE, F-93250 VILLEMOMBLE, FR
Format: Patent
Sprache:ger
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The invention relates to the compounds (I): in which: - RA and RA', RB and RB' represent hydrogen or alkyl (C1-4) or form a 5- or 6-membered heterocycle optionally substituted with an alkyl (C1-3), Y represents hydrogen or steroid in which: - R6 represents hydrogen, methyl, fluorine or chlorine, - R9 and R11 form a double bond, or R9 is hydrogen or fluorine and R11 is hydrogen, hydroxyl or oxo, - R16 represents hydrogen or methyl, - R17 represents hydrogen, hydroxyl or acyloxy, - the dotted lines at 1(2) and 6(7) represent a possible double bond, - the wavy line indicates a possible alpha or beta position, as well as their salts, to a process for their preparation and to the intermediates in this process, to their application as medicaments and to pharmaceutical compositions containing them.