Weitere antivirale Pyrimidin-Nukleosiden
Pyrimidine 4 min -thionucleosides of the formula (I) where B is a pyrimidine base; and either (a) R is hydrogen and R is hydroxy or fluoro, or (b) R is hydroxy and R is hydrogen, hydroxy or fluoro, or (c) R is fluoro and R is hydrogen or hydroxy, or (d) R and R together form a carbon-carbon bond; an...
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| creator | COE, PAUL, DEPARTMENT OF ISTRY, BIRMINGHAM B15 2TT, GB RAHIM, SAAD GEORGE, DEPARTMENT OF MEDICINAL ., LANGLEY COURT, BECKENHAM, KENT BR6 0TZ, GB WALKER, RICHARD, DEPARTMENT OF ISTRY, BIRMINGHAM B15 2TT, GB |
| description | Pyrimidine 4 min -thionucleosides of the formula (I) where B is a pyrimidine base; and either (a) R is hydrogen and R is hydroxy or fluoro, or (b) R is hydroxy and R is hydrogen, hydroxy or fluoro, or (c) R is fluoro and R is hydrogen or hydroxy, or (d) R and R together form a carbon-carbon bond; and physiologically functional derivatives thereof and processes for their production. Preferably, the base B is of the formula (II) wherein Y is hydroxy or amino, monoalkylamino or dialkylamino; and X is halogen, alkoxy, alkyl, haloalkyl, alkenyl, haloalkenyl, alkynyl, amino, monoalkylamino, dialkylamino, cyano or nitro. The compounds are useful in the treatment of viral infections. |
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Preferably, the base B is of the formula (II) wherein Y is hydroxy or amino, monoalkylamino or dialkylamino; and X is halogen, alkoxy, alkyl, haloalkyl, alkenyl, haloalkenyl, alkynyl, amino, monoalkylamino, dialkylamino, cyano or nitro. The compounds are useful in the treatment of viral infections.</description><edition>6</edition><language>ger</language><subject>CHEMISTRY ; DERIVATIVES THEREOF ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; NUCLEIC ACIDS ; NUCLEOSIDES ; NUCLEOTIDES ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS ; SUGARS</subject><creationdate>1996</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19961017&DB=EPODOC&CC=DE&NR=69025529T2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19961017&DB=EPODOC&CC=DE&NR=69025529T2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>COE, PAUL, DEPARTMENT OF ISTRY, BIRMINGHAM B15 2TT, GB</creatorcontrib><creatorcontrib>RAHIM, SAAD GEORGE, DEPARTMENT OF MEDICINAL ., LANGLEY COURT, BECKENHAM, KENT BR6 0TZ, GB</creatorcontrib><creatorcontrib>WALKER, RICHARD, DEPARTMENT OF ISTRY, BIRMINGHAM B15 2TT, GB</creatorcontrib><title>Weitere antivirale Pyrimidin-Nukleosiden</title><description>Pyrimidine 4 min -thionucleosides of the formula (I) where B is a pyrimidine base; and either (a) R is hydrogen and R is hydroxy or fluoro, or (b) R is hydroxy and R is hydrogen, hydroxy or fluoro, or (c) R is fluoro and R is hydrogen or hydroxy, or (d) R and R together form a carbon-carbon bond; and physiologically functional derivatives thereof and processes for their production. Preferably, the base B is of the formula (II) wherein Y is hydroxy or amino, monoalkylamino or dialkylamino; and X is halogen, alkoxy, alkyl, haloalkyl, alkenyl, haloalkenyl, alkynyl, amino, monoalkylamino, dialkylamino, cyano or nitro. The compounds are useful in the treatment of viral infections.</description><subject>CHEMISTRY</subject><subject>DERIVATIVES THEREOF</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>NUCLEIC ACIDS</subject><subject>NUCLEOSIDES</subject><subject>NUCLEOTIDES</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><subject>SUGARS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1996</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZNAIT80sSS1KVUjMK8ksyyxKzElVCKgsyszNTMnM0_Urzc5JzS_OTEnN42FgTUvMKU7lhdLcDEpuriHOHrqpBfnxqcUFicmpeakl8S6uZpYGRqamRpYhIUbGRCkCAFSUKYY</recordid><startdate>19961017</startdate><enddate>19961017</enddate><creator>COE, PAUL, DEPARTMENT OF ISTRY, BIRMINGHAM B15 2TT, GB</creator><creator>RAHIM, SAAD GEORGE, DEPARTMENT OF MEDICINAL ., LANGLEY COURT, BECKENHAM, KENT BR6 0TZ, GB</creator><creator>WALKER, RICHARD, DEPARTMENT OF ISTRY, BIRMINGHAM B15 2TT, GB</creator><scope>EVB</scope></search><sort><creationdate>19961017</creationdate><title>Weitere antivirale Pyrimidin-Nukleosiden</title><author>COE, PAUL, DEPARTMENT OF ISTRY, BIRMINGHAM B15 2TT, GB ; RAHIM, SAAD GEORGE, DEPARTMENT OF MEDICINAL ., LANGLEY COURT, BECKENHAM, KENT BR6 0TZ, GB ; WALKER, RICHARD, DEPARTMENT OF ISTRY, BIRMINGHAM B15 2TT, GB</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_DE69025529TT23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>ger</language><creationdate>1996</creationdate><topic>CHEMISTRY</topic><topic>DERIVATIVES THEREOF</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>NUCLEIC ACIDS</topic><topic>NUCLEOSIDES</topic><topic>NUCLEOTIDES</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><topic>SUGARS</topic><toplevel>online_resources</toplevel><creatorcontrib>COE, PAUL, DEPARTMENT OF ISTRY, BIRMINGHAM B15 2TT, GB</creatorcontrib><creatorcontrib>RAHIM, SAAD GEORGE, DEPARTMENT OF MEDICINAL ., LANGLEY COURT, BECKENHAM, KENT BR6 0TZ, GB</creatorcontrib><creatorcontrib>WALKER, RICHARD, DEPARTMENT OF ISTRY, BIRMINGHAM B15 2TT, GB</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>COE, PAUL, DEPARTMENT OF ISTRY, BIRMINGHAM B15 2TT, GB</au><au>RAHIM, SAAD GEORGE, DEPARTMENT OF MEDICINAL ., LANGLEY COURT, BECKENHAM, KENT BR6 0TZ, GB</au><au>WALKER, RICHARD, DEPARTMENT OF ISTRY, BIRMINGHAM B15 2TT, GB</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Weitere antivirale Pyrimidin-Nukleosiden</title><date>1996-10-17</date><risdate>1996</risdate><abstract>Pyrimidine 4 min -thionucleosides of the formula (I) where B is a pyrimidine base; and either (a) R is hydrogen and R is hydroxy or fluoro, or (b) R is hydroxy and R is hydrogen, hydroxy or fluoro, or (c) R is fluoro and R is hydrogen or hydroxy, or (d) R and R together form a carbon-carbon bond; and physiologically functional derivatives thereof and processes for their production. Preferably, the base B is of the formula (II) wherein Y is hydroxy or amino, monoalkylamino or dialkylamino; and X is halogen, alkoxy, alkyl, haloalkyl, alkenyl, haloalkenyl, alkynyl, amino, monoalkylamino, dialkylamino, cyano or nitro. The compounds are useful in the treatment of viral infections.</abstract><edition>6</edition><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY DERIVATIVES THEREOF HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SUGARS |
| title | Weitere antivirale Pyrimidin-Nukleosiden |
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