Verfahren zur Kombinierung von heterogenen Substanzgemischen mit Liposomen

In the process for combining heterogeneous substances, contained in a mixture, with liposomes, in particular allergenic substances, such as allergens and/or allergenic extracts, contained in an allergenic preparation, by adsorption at the surface of and/or incorporation in liposomes, which contain c...

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Bibliographische Detailangaben
Hauptverfasser: ROBLOT-TREUPEL, LILIANE, F-94320 THIAIS, FR, THAO, TRAN XUAN, F-92290 CHATENAY MALABRY, FR, MILLET-GENIN, ISABELLE, F-78370 PLAISIR, FR, PUISIEUX, FRANCIS, F-94700 MAISONS ALFORT, FR
Format: Patent
Sprache:ger
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Zusammenfassung:In the process for combining heterogeneous substances, contained in a mixture, with liposomes, in particular allergenic substances, such as allergens and/or allergenic extracts, contained in an allergenic preparation, by adsorption at the surface of and/or incorporation in liposomes, which contain cholesterol, a phospholipid and/or at least one ionic lipid which confers a positive or negative charge on the liposome, the mixture of heterogeneous substances is brought into contact with the liposome or its constituents, the pH of the whole being above or below the isoelectric point pI of the substances contained in the mixture, depending on whether the ionic lipid is positively or negatively charged, respectively.