1-HYDROXYVITAMIN D2-EPIMER UND DESSEN DERIVATE

The invention provides a new vitamin D2 compound, 1 alpha -hydroxy-24-epi-vitamin D2 and certain hydroxy-protected derivatives thereof. The new compound exhibits a distinctive activity pattern comprising high potency in stimulating intestinal calcium transport and little or no activity in inducing b...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	SCHNOES HEINRICH K., SCHNOES HEINRICH K., MADISON, WISCONSIN 53705, US, DELUCA HECTOR F., DELUCA HECTOR F., WISCONSIN 53531, US, PERLMAN KATO L., PERLMAN KATO L., MADISON, WISCONSIN 53711, US
Format:	Patent
Sprache:	ger
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The invention provides a new vitamin D2 compound, 1 alpha -hydroxy-24-epi-vitamin D2 and certain hydroxy-protected derivatives thereof. The new compound exhibits a distinctive activity pattern comprising high potency in stimulating intestinal calcium transport and little or no activity in inducing bone calcium mobilization or the differentiation of undifferentiated cells in culture, thereby evincing utility in the treatment of diseases characterized by loss of bone mass.