Immunstimulierende Guaninderivate, Zusammenstellungen und Verfahren

7,8-Disubstituted guanosine nucleoside derivatives are found to be potent immune response enhancing agents in human and animal cells. 7-Substituents are hydrocarbyl radicals having a length greater than ethyl and less than about decyl. 8-Substituents are =O, =S, =Se and =NCN. Compositions and method...

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Bibliographische Detailangaben
Hauptverfasser:	BELL, STANLEY, NARBERTH PENNSYLVANIA 19072, US, GOODMAN, MICHAELRANCHO SANTA FE CALIFORNIA 92067, US, WEIGLE, WILLIAM, CALIFORNIA 92075, US, ROBINS, ROLAND K., IRVINE CALIFORNIA 92715, US, HENNEN, WILLIAM J., BRYANT TEXAS 77802, US, CHEN, ROBERT, BELLE MEAD NEW JERSEY 08502, US
Format:	Patent
Sprache:	ger
Schlagworte:	CHEMISTRY DERIVATIVES THEREOF HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SUGARS
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Beschreibung
Zusammenfassung:	7,8-Disubstituted guanosine nucleoside derivatives are found to be potent immune response enhancing agents in human and animal cells. 7-Substituents are hydrocarbyl radicals having a length greater than ethyl and less than about decyl. 8-Substituents are =O, =S, =Se and =NCN. Compositions and methods of use are also disclosed.