In 2-Stellung substituierte Cumaranderivate
The present invention relates to a compound of the formula: wherein R is hydrogen or a lower alkyl; R is methyl which is substituted by a carboxy, alkoxycarbonyl, cyano, halogen, aryl or heterocyclic group or C2-15 chain-like hydrocarbon residue having no lower alkyl at the a-position which may be s...
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| creator | OHKAWA, SHIGENORI, TAKATSUKI OSAKA 569, JP FUKUDA, NAOHISA, KAWANISHI HYOGO 666-01, JP GOTO, GIICHI, TOYONO-GUN OSAKA 563-01, JP |
| description | The present invention relates to a compound of the formula: wherein R is hydrogen or a lower alkyl; R is methyl which is substituted by a carboxy, alkoxycarbonyl, cyano, halogen, aryl or heterocyclic group or C2-15 chain-like hydrocarbon residue having no lower alkyl at the a-position which may be substituted by a carboxy, alkoxycarbonyl, cyano, halogen, aryl or heterocyclic group; R is a lower alkyl; R is hydrogen or acyl; and R and R each is a lower alkyl or lower alkoxy, or R and R combinedly are butadienylene or a salt thereof. The compound (I) of the present invention has a strong 5- and 12-lipoxygenase inhibiting action, is of high safety and is useful as, among others, an agent for ameliorating circulatory system, an anti-allergic agent and a pharmaceutical agent for central nervous system |
| format | Patent |
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The compound (I) of the present invention has a strong 5- and 12-lipoxygenase inhibiting action, is of high safety and is useful as, among others, an agent for ameliorating circulatory system, an anti-allergic agent and a pharmaceutical agent for central nervous system</abstract><edition>5</edition><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | In 2-Stellung substituierte Cumaranderivate |
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