BENZIMIDAZOLE UND BENZOTHIAZOLE ALS INHIBITOREN DER MAP-KINASE

The present invention provides kinase inhibitors of Formula I: wherein W represents inter alia imidazol, oxazol, pyrazol, thiazol as triazol, which are substituted by phenyl or thienyl. The disclosed compounds inhibit p-38 kinase and are useful in the treatment of metastasis or rheumatoid arthritis

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Bibliographische Detailangaben
Hauptverfasser:	SHEPHERD, ALAN, SANCHEZ-MARTINEZ, S. A, BONJOUKLIAN, ROSANNE, HAMDOUCHI, HAMDOUCHI, WIKEL, HOWARD, MONTERO SALGADO, S. A, DE DIOS, S. A, PLEITE, S. A, YORK, SCHULENBURG, MARTIN CABREJAS, MARIA LILLY, DEL PRADO CATALINA, VIETH, MICHAL, DALLY, DEAN, DE DIEGO GOMEZ, EUGENIO LILLY, JARAMILLO, S. A, LI, TIECHAO, LOPEZ DE URALDE GARMENDIA, S. A
Format:	Patent
Sprache:	ger
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention provides kinase inhibitors of Formula I: wherein W represents inter alia imidazol, oxazol, pyrazol, thiazol as triazol, which are substituted by phenyl or thienyl. The disclosed compounds inhibit p-38 kinase and are useful in the treatment of metastasis or rheumatoid arthritis