GEFÄSSPROTHESE BESCHICHTET MIT EINEM FUNKTIONELLEM DEXTRAN-DERIVATE

The invention concerns a metal object for medical or surgical use, such as a prosthesis, for example an endovascular prosthesis (called stent) for percutaneous transluminal coronary angioplasty, comprising a metal substrate whereof the surface is coated partly at least with a polysaccharide compound...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: DARNIS, THIERRY, LEFRANC, OLIVIER, JOZEFONVICZ, JACQUELINE, AVRAMOGLOU, THIERRY, THERIN, MICHEL
Format: Patent
Sprache:ger
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Beschreibung
Zusammenfassung:The invention concerns a metal object for medical or surgical use, such as a prosthesis, for example an endovascular prosthesis (called stent) for percutaneous transluminal coronary angioplasty, comprising a metal substrate whereof the surface is coated partly at least with a polysaccharide compound. The invention is characterised in that the polysaccharide compound is covalently bound, via a plurality of grafting arms, comprising each at least a silane unit, bound on one side to the metal substrate by an -O- metal bond, and on the other side, directly or indirectly, by a covalent -NH- bond, with the polysaccharide compound.