VERFAHREN ZUR HERSTELLUNG VON CANDESARTAN CILEXETIL

The invention encompasses processes for the synthesis of cilexetil trityl candesartan from the reaction of trityl candesartan with cilexetil halide in the presence of a base and a low boiling organic solvent. Optionally, the reaction may be conducted in the presence of a phase transfer catalyst.

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Bibliographische Detailangaben
Hauptverfasser: DOLITZKY, BEN-ZION, FEDOTEV, BORIS, ETINGER, MARINA YU
Format: Patent
Sprache:ger
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Beschreibung
Zusammenfassung:The invention encompasses processes for the synthesis of cilexetil trityl candesartan from the reaction of trityl candesartan with cilexetil halide in the presence of a base and a low boiling organic solvent. Optionally, the reaction may be conducted in the presence of a phase transfer catalyst.