HETEROCYCLISCHE SULFONAMIDE ALS INHIBITOREN DER BETA-AMYLOID-PRODUKTION

Compounds of Formula (I), wherein R1, R2, R3, R4, R5, R6, T, W, X, Y and Z are as defined herein are provided, together with pharmaceutically acceptable salt, hydrates and/or prodrugs thereof. Methods of using these compounds for inhibiting beta amyloid production and for treatment of Alzheimer'...

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Hauptverfasser: DIAMANITIS, GEORGE, MOORE, WILLIAM JAY, STOCK, JOSEPH RAYMOND, KREFT, ANTHONY FRANK, WOLLER, KEVIN ROGER, CASEBIER, DAVID SCOTT, COLE, DEREK CECIL, KURBRAK, DENNIS MICHAEL, KUTTERER, KRISTINA MARTHA
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creator DIAMANITIS, GEORGE
MOORE, WILLIAM JAY
STOCK, JOSEPH RAYMOND
KREFT, ANTHONY FRANK
WOLLER, KEVIN ROGER
CASEBIER, DAVID SCOTT
COLE, DEREK CECIL
KURBRAK, DENNIS MICHAEL
KUTTERER, KRISTINA MARTHA
description Compounds of Formula (I), wherein R1, R2, R3, R4, R5, R6, T, W, X, Y and Z are as defined herein are provided, together with pharmaceutically acceptable salt, hydrates and/or prodrugs thereof. Methods of using these compounds for inhibiting beta amyloid production and for treatment of Alzheimer's disease and Down's syndrome are described.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title HETEROCYCLISCHE SULFONAMIDE ALS INHIBITOREN DER BETA-AMYLOID-PRODUKTION
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