HETEROCYCLISCHE SULFONAMIDE ALS INHIBITOREN DER BETA-AMYLOID-PRODUKTION

HETEROCYCLISCHE SULFONAMIDE ALS INHIBITOREN DER BETA-AMYLOID-PRODUKTION

Compounds of Formula (I), wherein R1, R2, R3, R4, R5, R6, T, W, X, Y and Z are as defined herein are provided, together with pharmaceutically acceptable salt, hydrates and/or prodrugs thereof. Methods of using these compounds for inhibiting beta amyloid production and for treatment of Alzheimer'...

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Bibliographische Detailangaben
Hauptverfasser: DIAMANITIS, GEORGE, MOORE, WILLIAM JAY, STOCK, JOSEPH RAYMOND, KREFT, ANTHONY FRANK, WOLLER, KEVIN ROGER, CASEBIER, DAVID SCOTT, COLE, DEREK CECIL, KURBRAK, DENNIS MICHAEL, KUTTERER, KRISTINA MARTHA
Format: Patent
Sprache:ger
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:Compounds of Formula (I), wherein R1, R2, R3, R4, R5, R6, T, W, X, Y and Z are as defined herein are provided, together with pharmaceutically acceptable salt, hydrates and/or prodrugs thereof. Methods of using these compounds for inhibiting beta amyloid production and for treatment of Alzheimer's disease and Down's syndrome are described.