NEUE AMIDINBENZYLAMIN-DERIVATE UND IHRE VERWENDUNG ALS THROMBIN-INHIBITOREN

There is provided compounds of formula Iwherein R1, R2, Y, R3 and R4 have meanings given in the description which are useful as, or as prodrugs of, competitive inhibitors of trypsin-like proteases, such as thrombin, and in particular in the treatment of conditions where inhibition of thrombin is req...

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Bibliographische Detailangaben
Hauptverfasser: NYSTROEM, JAN-ERIK, INGHARDT, TORD
Format: Patent
Sprache:ger
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Zusammenfassung:There is provided compounds of formula Iwherein R1, R2, Y, R3 and R4 have meanings given in the description which are useful as, or as prodrugs of, competitive inhibitors of trypsin-like proteases, such as thrombin, and in particular in the treatment of conditions where inhibition of thrombin is required (e.g. thrombosis) or as anticoagulants.