New bi:phenyl-methyl-benzimidazole derivs

1-Biphenylylmethyl-benzimidazole derivs. of formula (I) and their tautomers and salts are new: R1 = F, Cl, Br, 1-3C alkyl or CF3; R2 = opt. substd. C-bonded 5-membered heteroaryl contg. one heteroatom (NH, O or S) or two heteroatoms (NH and O, S or N), opt. fused to another ring; a pyrrolidino, pipe...

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Hauptverfasser:	RIES, UWE. DR., 88400 BIBERACH, DE, HAUEL, NORBERT. DR., 88433 SMERHOFEN, DE, MEEL, JACPUES VAN., 88441 MITTELBIBERACH, DE, WIENEN, WOLFGANG-BIOL. DR., 88437 AEPFINGEN, DE, MIHM, GERHARD. DR., 88440 BIBERACH, DE, ENTZEROTH, MICHAEL. DR., 88447 WARTHAUSEN, DE
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Sprache:	eng ; ger
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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creator	RIES, UWE. DR., 88400 BIBERACH, DE HAUEL, NORBERT. DR., 88433 SMERHOFEN, DE MEEL, JACPUES VAN., 88441 MITTELBIBERACH, DE WIENEN, WOLFGANG-BIOL. DR., 88437 AEPFINGEN, DE MIHM, GERHARD. DR., 88440 BIBERACH, DE ENTZEROTH, MICHAEL. DR., 88447 WARTHAUSEN, DE
description	1-Biphenylylmethyl-benzimidazole derivs. of formula (I) and their tautomers and salts are new: R1 = F, Cl, Br, 1-3C alkyl or CF3; R2 = opt. substd. C-bonded 5-membered heteroaryl contg. one heteroatom (NH, O or S) or two heteroatoms (NH and O, S or N), opt. fused to another ring; a pyrrolidino, piperidino or hexamethylenimino gp. in which a CH2 gp. is replaced by CO or SO2; opt. substd. maleimido (opt. substd. by 1-3C alkyl or phenyl), or opt. substd. 2,4-dioxo-3-imidazolidinyl; R3 = 1-4C alkyl, 3-5C cycloalkyl, 1-3C alkoxy or 1-3C alkylthio; R4 = opt. substd. amino, substd. sulphonyl, C(NH)NHOH; 2,4-dioxo-5-thiazolidinylidenemethyl; or 5-oxo-1,2,4-oxadiazol-3-yl.
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C-bonded 5-membered heteroaryl contg. one heteroatom (NH, O or S) or two heteroatoms (NH and O, S or N), opt. fused to another ring; a pyrrolidino, piperidino or hexamethylenimino gp. in which a CH2 gp. is replaced by CO or SO2; opt. substd. maleimido (opt. substd. by 1-3C alkyl or phenyl), or opt. substd. 2,4-dioxo-3-imidazolidinyl; R3 = 1-4C alkyl, 3-5C cycloalkyl, 1-3C alkoxy or 1-3C alkylthio; R4 = opt. substd. amino, substd. sulphonyl, C(NH)NHOH; 2,4-dioxo-5-thiazolidinylidenemethyl; or 5-oxo-1,2,4-oxadiazol-3-yl.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1995</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZND0Sy1XSMq0KshIzavM0c1NLckAUkmpeVWZuZkpiVX5OakKKalFmWXFPAysaYk5xam8UJqbQcHNNcTZQze1ID8-tbggMTk1L7Uk3sXVxMTAwsTS3NHQmAglAMsxKI4</recordid><startdate>19950921</startdate><enddate>19950921</enddate><creator>RIES, UWE. 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DR., 88440 BIBERACH, DE</creatorcontrib><creatorcontrib>ENTZEROTH, MICHAEL. DR., 88447 WARTHAUSEN, DE</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>RIES, UWE. DR., 88400 BIBERACH, DE</au><au>HAUEL, NORBERT. DR., 88433 SMERHOFEN, DE</au><au>MEEL, JACPUES VAN., 88441 MITTELBIBERACH, DE</au><au>WIENEN, WOLFGANG-BIOL. DR., 88437 AEPFINGEN, DE</au><au>MIHM, GERHARD. DR., 88440 BIBERACH, DE</au><au>ENTZEROTH, MICHAEL. DR., 88447 WARTHAUSEN, DE</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>New bi:phenyl-methyl-benzimidazole derivs</title><date>1995-09-21</date><risdate>1995</risdate><abstract>1-Biphenylylmethyl-benzimidazole derivs. of formula (I) and their tautomers and salts are new: R1 = F, Cl, Br, 1-3C alkyl or CF3; R2 = opt. substd. 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subjects	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title	New bi:phenyl-methyl-benzimidazole derivs
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