New bi:phenyl-methyl-benzimidazole derivs

1-Biphenylylmethyl-benzimidazole derivs. of formula (I) and their tautomers and salts are new: R1 = F, Cl, Br, 1-3C alkyl or CF3; R2 = opt. substd. C-bonded 5-membered heteroaryl contg. one heteroatom (NH, O or S) or two heteroatoms (NH and O, S or N), opt. fused to another ring; a pyrrolidino, pipe...

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Bibliographische Detailangaben
Hauptverfasser:	RIES, UWE. DR., 88400 BIBERACH, DE, HAUEL, NORBERT. DR., 88433 SMERHOFEN, DE, MEEL, JACPUES VAN., 88441 MITTELBIBERACH, DE, WIENEN, WOLFGANG-BIOL. DR., 88437 AEPFINGEN, DE, MIHM, GERHARD. DR., 88440 BIBERACH, DE, ENTZEROTH, MICHAEL. DR., 88447 WARTHAUSEN, DE
Format:	Patent
Sprache:	eng ; ger
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	1-Biphenylylmethyl-benzimidazole derivs. of formula (I) and their tautomers and salts are new: R1 = F, Cl, Br, 1-3C alkyl or CF3; R2 = opt. substd. C-bonded 5-membered heteroaryl contg. one heteroatom (NH, O or S) or two heteroatoms (NH and O, S or N), opt. fused to another ring; a pyrrolidino, piperidino or hexamethylenimino gp. in which a CH2 gp. is replaced by CO or SO2; opt. substd. maleimido (opt. substd. by 1-3C alkyl or phenyl), or opt. substd. 2,4-dioxo-3-imidazolidinyl; R3 = 1-4C alkyl, 3-5C cycloalkyl, 1-3C alkoxy or 1-3C alkylthio; R4 = opt. substd. amino, substd. sulphonyl, C(NH)NHOH; 2,4-dioxo-5-thiazolidinylidenemethyl; or 5-oxo-1,2,4-oxadiazol-3-yl.