New benzimidazol-1-yl-methyl-bi:phenyl derivs

Benzimidazole derivs. of formula (I) and their salts are new. R1 is 1-3C alkyl, H, F, Cl or Br; R2 is e.g, oxazol-4-yl, thiazol-4-yl (these 2 opt. substd. in position 2- with 1-6C alkyl or Ph), imidazol-4-yl (opt. substd. in position 2- with 1-6C alkyl or Ph or in position 1- with 1-7C alkl (itself...

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Bibliographische Detailangaben
Hauptverfasser:	RIES, UWE. DR., 7950 BIBERACH, DE, ENTZEROTH, MICHAEL. DR., 7951 WARTHAUSEN, DE, MEEL, JACQUES VAN., 7951 MITTELBIBERACH, DE, NARR, BERTHOLD. DR., 7950 BIBERACH, DE, HAUEL, NORBERT. DR., 7951 EBERHARDZELL, DE, WIENEN, WOLFGANG-BIO. DR., 7951 AEPFINGEN, DE
Format:	Patent
Sprache:	eng ; ger
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Benzimidazole derivs. of formula (I) and their salts are new. R1 is 1-3C alkyl, H, F, Cl or Br; R2 is e.g, oxazol-4-yl, thiazol-4-yl (these 2 opt. substd. in position 2- with 1-6C alkyl or Ph), imidazol-4-yl (opt. substd. in position 2- with 1-6C alkyl or Ph or in position 1- with 1-7C alkl (itself opt. substd. in any position with carboxy, alkoxycarbonyl etc., 2-4C alkyl (itself opt. substd. in position 2-, 3- or 4- with OH, alkoxy, alkoxyalkoxy, etc., alkyl (itself opt. substd. with CF3, 3-7C cycloalkyl or Ph (itself opt. mono- or di-substd. with F, Cl, CF3, Me or MeO)), alkyl (itself opt. mono- or di-substd. with Ph or mono substd. with 3-7C cycloalkyl)), where, unless otherwise stated alkyl and alkoxy gps. contain 1-3C; R3 is 2-4C alkyl, 2-3C alkoxy, 2-3C alkylthio, cyclopropyl or cyclobutyl; R4 is eg., a gp. capable of being converted in vivo to carboxy in cpds. (Ia) or carboxy, CN, 1H-tetrazolyl etc..