3,4-CYCLOAMIDRAZONE, VERFAHREN ZU IHRER HERSTELLUNG UND DIESE ENTHALTENDE PHARMAZEUTISCHE MITTEL

3,4-CYCLOAMIDRAZONE, VERFAHREN ZU IHRER HERSTELLUNG UND DIESE ENTHALTENDE PHARMAZEUTISCHE MITTEL

The invention relates to partly novel 3,4-cycloamidrazones, a process for producing them and their use in pharmaceutical preparations. The 3,4-cycloamidrazones are lactam-aryl hydrazones and cycloimide-aryl hydrazones. They are produced by the reaction of activated lactam and cycloimide derivatives...

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Bibliographische Detailangaben
Hauptverfasser: NUHN, PETER, DR., O-7027 LEIPZIG, DE, SCHNEIDER, RUDOLF., O-4020 HALLE, DE, MICHAEL, ANTJE, O-3600 HALBERSTADT, DE, SCHWALBE, ANDREAS, O-9417 ZWOENITZ, DE, LETTAU, HERBERT., O-4090 HALLE-NEUSTADT, (VERSTORBEN), DE
Format: Patent
Sprache:ger
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:The invention relates to partly novel 3,4-cycloamidrazones, a process for producing them and their use in pharmaceutical preparations. The 3,4-cycloamidrazones are lactam-aryl hydrazones and cycloimide-aryl hydrazones. They are produced by the reaction of activated lactam and cycloimide derivatives with aryl hydrazines or aryl hydrazine hydrochlorides. The 3,4-cycloamidrazones of the invention are highly effective lipoxygenase inhibitors and may be used in medicaments to treat all kinds of inflammations, allergic conditions, asthma, bronchitis and psoriasis.