O-glycosylated alpha interferon

Alpha-interferon (IFNalpha) which is O-glycosylated and has the biological and/or immunological properties of IFN alpha (2) is new. Specified are O-glycosylate IFNalpha-2a,-2b and -2c. More specifically, the prod. is glycosylated at Thr-106, esp. by Gal-GalNac (including its mono- or di-sialylated d...

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Hauptverfasser:	AHORN, HORST., WEIGELSDORF, AT, KALSNER, INGE., TORONTO, ONTARIO, CA, MAURER-FOGY, INGRID., WIEN, AT, ADOLF, GUENTHER., WIEN, AT
Format:	Patent
Sprache:	eng ; ger
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	Alpha-interferon (IFNalpha) which is O-glycosylated and has the biological and/or immunological properties of IFN alpha (2) is new. Specified are O-glycosylate IFNalpha-2a,-2b and -2c. More specifically, the prod. is glycosylated at Thr-106, esp. by Gal-GalNac (including its mono- or di-sialylated derivs.) or Gal-(Gal-GlcNAc)-GalNac.