SUBSTITUIERTE (CHINOLIN-2-YL-METHOXY)PHENYL-CARBONYLHARNSTOFFE

Substituted (quinolin-2-ylmethoxy)phenylcarbonylureas can be prepared by reaction of substituted (quinolin-2-ylmethoxy)anilines with isocyanates and, if appropriate, subsequent alkylation. The substituted (quinolin-2-ylmethoxy)phenylcarbonylureas can be employed as active substances in medicaments,...

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Hauptverfasser: RADDATZ, SIEGFRIED. DR., 5000 KOELN, DE, KOHLSDORFER, CHRISTIAN-BIOL. DR., 5042 ERFTSTADT, DE, FRUCHTMANN, ROMANIS-BIOL., 5000 KOELN, DE, MUELLER-PEDDINGHAUS, REINER, THEISEN, PIA-OEC.TROPH. DR., 5060 BERGISCH GLADBACH, DE, MOHRS, KLAUS. DR., 5600 WUPPERTAL, DE, FUGMANN, BURKHARD. DR., 5603 WUELFRATH, DE
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Zusammenfassung:Substituted (quinolin-2-ylmethoxy)phenylcarbonylureas can be prepared by reaction of substituted (quinolin-2-ylmethoxy)anilines with isocyanates and, if appropriate, subsequent alkylation. The substituted (quinolin-2-ylmethoxy)phenylcarbonylureas can be employed as active substances in medicaments, in particular for the inhibition of enzymatic reactions in the context of arachidonic acid metabolism.