14,17(ALPHA)-ETHENO- UND ETHANOESTRATRIENE, VERFAHREN ZUR HERSTELLUNG DIESER VERBINDUNGEN, SOWIE IHRE VERWENDUNG ZUR HERSTELLUNG VON ARZNEIMITTELN

14,17(ALPHA)-ETHENO- UND ETHANOESTRATRIENE, VERFAHREN ZUR HERSTELLUNG DIESER VERBINDUNGEN, SOWIE IHRE VERWENDUNG ZUR HERSTELLUNG VON ARZNEIMITTELN

14,17 alpha -etheno- and ethanooestratrienes of the general formula I in which X is a -CH2-CH2- or bridge,   R is a hydrogen atom, a C1-C15-acyl, benzoyl, C1-C15-alkyl, C3-C9-cycloalkyl or alkylcycloalkyl group and   R is the group where R and R are, independently of one another, a hydrogen atom or...

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Hauptverfasser: NISHINO, YUKISHIGE., 1000 BERLIN, DE, BOHLMANN, ROLF, KUENZER, HERMANN, WIECHERT, RUDOLF, DR, HENDERSON, DAVID, SCHNEIDER, MARTIN
Format: Patent
Sprache:ger
Schlagworte:
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
STEROIDS
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Zusammenfassung:14,17 alpha -etheno- and ethanooestratrienes of the general formula I in which X is a -CH2-CH2- or bridge,   R is a hydrogen atom, a C1-C15-acyl, benzoyl, C1-C15-alkyl, C3-C9-cycloalkyl or alkylcycloalkyl group and   R is the group where R and R are, independently of one another, a hydrogen atom or a straight-chain or branched, optionally partially or completely fluorinated C1-C8-alkyl group, a process for the preparation thereof, pharmaceutical products containing these compounds, and the use thereof for producing pharmaceuticals, are described. The compounds have potent antioestrogenic activity.