MAGNETISCHE PROTEIN-KONJUGATE, VERFAHREN ZU IHRER HERSTELLUNG UND IHRE VERWENDUNG

The invention relates to magnetic protein conjugates of the general formula I M-NH-CO-(CH2)n-S-SP I with n = 1-6, preferably with n = 2 or 3, in which M is a dispersible, magnetically reacting material or particle which carries amino groups, and P is a protein, to a method for making them and to the...

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Hauptverfasser: HERMENTIN, PETER., 3550 MARBURG, DE, SEILER, FRIEDRICH ROBERT., 3550 MARBURG, DE, FRANSSEN, UDO, KURRLE, ROLAND, DOENGES, REINER, 3554 GLADENBACH, DE, ENSSLE, KARLHEINZ
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creator HERMENTIN, PETER., 3550 MARBURG, DE
SEILER, FRIEDRICH ROBERT., 3550 MARBURG, DE
FRANSSEN, UDO
KURRLE, ROLAND
DOENGES, REINER, 3554 GLADENBACH, DE
ENSSLE, KARLHEINZ
description The invention relates to magnetic protein conjugates of the general formula I M-NH-CO-(CH2)n-S-SP I with n = 1-6, preferably with n = 2 or 3, in which M is a dispersible, magnetically reacting material or particle which carries amino groups, and P is a protein, to a method for making them and to their use for the specific removal of cells or soluble antigens, receptors, substrates, cofactors or carbohydrate determinants from aqueous salt solutions or body fluids or as part of a diagnostic method or as diagnostic aid, preferably for the removal of cells, preferably for bone marrow depletion or for HLA typing.
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recordid cdi_epo_espacenet_DE3919923A1
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PHYSICS
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
TESTING
VINEGAR
WINE
title MAGNETISCHE PROTEIN-KONJUGATE, VERFAHREN ZU IHRER HERSTELLUNG UND IHRE VERWENDUNG
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