MAGNETISCHE PROTEIN-KONJUGATE, VERFAHREN ZU IHRER HERSTELLUNG UND IHRE VERWENDUNG

The invention relates to magnetic protein conjugates of the general formula I M-NH-CO-(CH2)n-S-SP I with n = 1-6, preferably with n = 2 or 3, in which M is a dispersible, magnetically reacting material or particle which carries amino groups, and P is a protein, to a method for making them and to the...

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Bibliographische Detailangaben
Hauptverfasser:	HERMENTIN, PETER., 3550 MARBURG, DE, SEILER, FRIEDRICH ROBERT., 3550 MARBURG, DE, FRANSSEN, UDO, KURRLE, ROLAND, DOENGES, REINER, 3554 GLADENBACH, DE, ENSSLE, KARLHEINZ
Format:	Patent
Sprache:	ger
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	The invention relates to magnetic protein conjugates of the general formula I M-NH-CO-(CH2)n-S-SP I with n = 1-6, preferably with n = 2 or 3, in which M is a dispersible, magnetically reacting material or particle which carries amino groups, and P is a protein, to a method for making them and to their use for the specific removal of cells or soluble antigens, receptors, substrates, cofactors or carbohydrate determinants from aqueous salt solutions or body fluids or as part of a diagnostic method or as diagnostic aid, preferably for the removal of cells, preferably for bone marrow depletion or for HLA typing.