SUBSTITUIERTE (CHINOLIN-2-YL-METHOXY)PHENYL-N,N'-SULFONYLHARNSTOFFE, VERFAHREN ZU IHRER HERSTELLUNG UND IHRE VERWENDUNG IN ARZNEIMITTELN

Substituted (quinolin-2-ylmethoxy)phenyl-N,N'-sulphonylureas can be prepared by reaction of (quinolin-2-ylmethoxy)phenylamines with sulphonyl isocyanates, or by reaction of appropriately protected hydroxyanilines with sulphonyl isocyanates and then, after removal of the protective group, with h...

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Hauptverfasser: MUELLER-PEDDINGHAUS, REINER, DR, RADDATZ, SIEGFRIED. DR., 5000 KOELN, DE, KOHLSDORFER, CHRISTIAN-BIOL. DR., 5042 ERFTSTADT, DE, THEISEN, PIA-OEC.TROP.., 5060 BERGISCH GLADBACH, DE, FRUCHTMANN, ROMANIS-BIOL., 5000 KOELN, DE, MOHRS, KLAUS. DR., 5600 WUPPERTAL, DE
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creator MUELLER-PEDDINGHAUS, REINER, DR
RADDATZ, SIEGFRIED. DR., 5000 KOELN, DE
KOHLSDORFER, CHRISTIAN-BIOL. DR., 5042 ERFTSTADT, DE
THEISEN, PIA-OEC.TROP.., 5060 BERGISCH GLADBACH, DE
FRUCHTMANN, ROMANIS-BIOL., 5000 KOELN, DE
MOHRS, KLAUS. DR., 5600 WUPPERTAL, DE
description Substituted (quinolin-2-ylmethoxy)phenyl-N,N'-sulphonylureas can be prepared by reaction of (quinolin-2-ylmethoxy)phenylamines with sulphonyl isocyanates, or by reaction of appropriately protected hydroxyanilines with sulphonyl isocyanates and then, after removal of the protective group, with halomethylquinolines, or by reaction of (quinolin-2-ylmethoxy)phenyl-N,N'-sulphonylureas with sulphonyl halides. The substituted (quinolin-2-ylmethoxy)phenyl- N,N'-sulphonylureas can be employed as active substances in medicaments, in particular as lipoxygenase inhibitors.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title SUBSTITUIERTE (CHINOLIN-2-YL-METHOXY)PHENYL-N,N'-SULFONYLHARNSTOFFE, VERFAHREN ZU IHRER HERSTELLUNG UND IHRE VERWENDUNG IN ARZNEIMITTELN
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