SUBSTITUIERTE (CHINOLIN-2-YL-METHOXY)PHENYL-N,N'-SULFONYLHARNSTOFFE, VERFAHREN ZU IHRER HERSTELLUNG UND IHRE VERWENDUNG IN ARZNEIMITTELN

Substituted (quinolin-2-ylmethoxy)phenyl-N,N'-sulphonylureas can be prepared by reaction of (quinolin-2-ylmethoxy)phenylamines with sulphonyl isocyanates, or by reaction of appropriately protected hydroxyanilines with sulphonyl isocyanates and then, after removal of the protective group, with h...

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Hauptverfasser:	MUELLER-PEDDINGHAUS, REINER, DR, RADDATZ, SIEGFRIED. DR., 5000 KOELN, DE, KOHLSDORFER, CHRISTIAN-BIOL. DR., 5042 ERFTSTADT, DE, THEISEN, PIA-OEC.TROP.., 5060 BERGISCH GLADBACH, DE, FRUCHTMANN, ROMANIS-BIOL., 5000 KOELN, DE, MOHRS, KLAUS. DR., 5600 WUPPERTAL, DE
Format:	Patent
Sprache:	ger
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:	Substituted (quinolin-2-ylmethoxy)phenyl-N,N'-sulphonylureas can be prepared by reaction of (quinolin-2-ylmethoxy)phenylamines with sulphonyl isocyanates, or by reaction of appropriately protected hydroxyanilines with sulphonyl isocyanates and then, after removal of the protective group, with halomethylquinolines, or by reaction of (quinolin-2-ylmethoxy)phenyl-N,N'-sulphonylureas with sulphonyl halides. The substituted (quinolin-2-ylmethoxy)phenyl- N,N'-sulphonylureas can be employed as active substances in medicaments, in particular as lipoxygenase inhibitors.