2,5,6,7-TETRANOR-4,8-INTER-m-PHENYLEN 2-PGI-DERIVATE, VERFAHREN ZUR HERSTELLUNG UND DEREN VERWENDUNG

2,5,6,7-TETRANOR-4,8-INTER-m-PHENYLEN 2-PGI-DERIVATE, VERFAHREN ZUR HERSTELLUNG UND DEREN VERWENDUNG

2,5,6,7-Tetranor-4,8-inter-m-phenylene PGI2 derivatives such as 16-methyl-2,5,6,7-tetranor-4,8-inter-m-phenylene PGI2 and its methyl ester, 17-methyl-2,5,6,7-tetranor-4,8-inter-m-phenylene PGI2 and its methyl ester, 15-phenyl-2,5,6,7,16,17,18,19,20-nonanor-4,8-inter-m-phenylene PGI2, 16-methyl-17-ph...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: WAKITA, HISANORI, KAMAKURA-SHI KANAGAWA 248, JP, OHNO, KIYOTAKA, FUJISAWA-SHI KANAGAWA 251, JP, TAKAHASHI, TOSHIYA, KANAGAWA 248, JP, OHTAKE, ATSUSHI, KAMAKURA-SHI KANAGAWA 248, JP, NISHIO, SHINTARO, EBINA-SHI KANAGAWA 243-04, JP
Format: Patent
Sprache:ger
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:2,5,6,7-Tetranor-4,8-inter-m-phenylene PGI2 derivatives such as 16-methyl-2,5,6,7-tetranor-4,8-inter-m-phenylene PGI2 and its methyl ester, 17-methyl-2,5,6,7-tetranor-4,8-inter-m-phenylene PGI2 and its methyl ester, 15-phenyl-2,5,6,7,16,17,18,19,20-nonanor-4,8-inter-m-phenylene PGI2, 16-methyl-17-phenyl-2,5,6,7,18,19,20-heptanor-4,8-inter-m-phenylene PGI2, 16,16-dimethyl-17-phenyl-2,5,6,7,18,19,20-heptanor-4,8-inter-m-phenylene PGI2, 16-methyl-16-phenoxy-2,5,6,7,17,18,19,20-octanor-4,8-inter-m-phenylene PGI2, 16-methyl-16-phenoxy-2,5,6,7,18,19,20-heptanor-4,8-inter-m-phenylene PGI2 and its methyl ester and 3-decarboxy-3-hydroxymethyl-16-methyl-16-phenoxy-2,5,6,7,18,19,20-hept anor-4,8-inter-m-phenylene PGI2, useful as medicines, are disclosed. These derivatives are useful as, for example, antiulceric agents, hypotensives, and antithrombotic agents.