WASSERLÖSLICHE HYALURONSÄUREDERIVATE

A method for making a water insouble bicompatible gel includes activating HA with an activating agent to form activated HA, and reacting the activated HA with a nucleophile, under conditions producing the water insoluble bicompatible gel. Also, a method for making a water insoluble biocompatible fil...

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Hauptverfasser: HAMILTON, RAYMOND, G., SOMERVILLE, MA 02143, US, ACHARYA, RAKSHA, A., NORTHBORO, MA 01532, US, FOX, ELLEN, M., CRANSTON, RI 02920, US, WALTS, ALAN, E., BROOKLINE, MA 02146, US
Format: Patent
Sprache:ger
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Zusammenfassung:A method for making a water insouble bicompatible gel includes activating HA with an activating agent to form activated HA, and reacting the activated HA with a nucleophile, under conditions producing the water insoluble bicompatible gel. Also, a method for making a water insoluble biocompatible film includes providing a biocompatible gel made according to the above method, and drying the gel or compressing the gel under conditions permitting escape of water from the gel. Also, a water insoluble composition including HA is prepared without the use of any bifunctional or polyfunctional nucleophile.