DIPHENYLMETHAN-DERIVATE, ARZNEIMITTEL UND VERWENDUNG

Diphenyl-methane derivs. of formula (I) are new, (where R1 and R2 each = H, OH or lower alkoxy; U = -CXY or =N-O-W; X = H, CN or -COR6; R6 = OH or NH2; Y = -R10-COOR3, -CONR4R5, -CH2NHSO2-C6H5 or -C(R8)=NR7; R3 = H or lower alkoxy; R10 = opt. branched 1-3C alkylene; R4 and R5 each = H, lower alkyl o...

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Bibliographische Detailangaben
Hauptverfasser:	ABE, SHINYA, USHIKU-SHI IBARAKI, JP, SUZUKI, TAKESHI, USHIKU-SHI IBARAKI, JP, OKANO, KAZUO, TSUKUBA-GUNN IBARAKI, JP, YAMAGISHI, YOUJI, NIIHARI-GUN IBARAKI, JP, IKUTA, HIRONORI, USHIKU-SHI IBARAKI, JP, HAYASHI, KENJI, TSUKUBA-SHI IBARAKI, JP, HARADA, KOUKICHI, TSUKUBA-GUN IBARAKI, JP, MIYAMOTO, MITSUAKI, NIIHARI-GUN IBARAKI, JP, NAKAMOTO, KOUJI, TSUCHIURA-SHI IBARAKI, JP, YOSHIMURA, HIROYUKI, TSUKUBA-GUN IBARAKI, JP, FUJIMORI, TOHRU, TSUKUBA-GUN IBARAKI, JP, YAMATSU, ISAO, USHIKU-SHI IBARAKI, JP, AKASAKA, KOZO, USHIKU-SHI IBARAKI, JP
Format:	Patent
Sprache:	ger
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Diphenyl-methane derivs. of formula (I) are new, (where R1 and R2 each = H, OH or lower alkoxy; U = -CXY or =N-O-W; X = H, CN or -COR6; R6 = OH or NH2; Y = -R10-COOR3, -CONR4R5, -CH2NHSO2-C6H5 or -C(R8)=NR7; R3 = H or lower alkoxy; R10 = opt. branched 1-3C alkylene; R4 and R5 each = H, lower alkyl or lower arylalkyl; R7 = lower alkoxy or aryl; R8 = -VR9; V = O, S or N; R9 = alkyl or aryl; W = -CH2-CO-CH2-COOR13, -CH2-C(=NOR14)-CH2-COOR15, -CH(CN)-(CH2)q-COOR16 or -(CH2)p-Z; R13 = H or lower alkyl; R14 = lower alkyl; R15 = H or lower alkyl; R16 = H or lower alkyl; q = 1-3; Z = -SH, -SCN or a monovalent gp. derived from a 5- or 6-membered ring opt. substd. by a ring with 1 or more S in the ring; p = 1 or 2.