NEUE HETEROARYLETHANOLAMINE, DIESE VERBINDUNGEN ENTHALTENDE ARZNEIMITTEL UND VERFAHREN ZU IHRER HERSTELLUNG

Pyridylethanolamines of the formula in which R denotes a carboxymethoxy, carbomethoxymethoxy, ethoxycarbonylmethoxy or 2-hydroxyethoxy group, their optical isomers, their diastereomers and their acid addition salts. The novel compounds of the above formula I, their optical isomers and their diastere...

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Hauptverfasser: RUPPRECHT,ECKHARD,-BIOL.DR, SAUTER,ROBERT,.DR, HURNAUS,RUDOLF,.DR, GRELL,WOLFGANG,.DR, MARK,MICHAEL,DR, REIFFEN,MANFRED,.DR
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Sprache:ger
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Zusammenfassung:Pyridylethanolamines of the formula in which R denotes a carboxymethoxy, carbomethoxymethoxy, ethoxycarbonylmethoxy or 2-hydroxyethoxy group, their optical isomers, their diastereomers and their acid addition salts. The novel compounds of the above formula I, their optical isomers and their diastereomers and also their acid addition salts, in particular their physiologically tolerable acid addition salts with inorganic or organic acids, have useful pharmacological properties, namely an effect on the metabolism, preferably a hypoglycaemic and body fat-reducing effect, and also a lowering effect on the atherogenic beta -lipoproteins VLDL and LDL. The novel compounds of the above formula I can be prepared by processes which are known per se.