MEDICAGENSAEURE-DERIVATE ENTHALTENDE MITTEL ZUR BEHANDLUNG VON PILZINFEKTIONEN

Medicagenic acid and derivatives thereof of the general formula wherein R1 is H or acetyl; R2 is H, acetyl, beta -glucopyranosyl or alpha -glucopyrano (1-4) beta -glucopyranosyl and R3 is H or C1-6 alkyl are useful antifungal agents in combination with suitable carriers or diluents. They are active...

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Bibliographische Detailangaben
Hauptverfasser:	LEVY,MORDEKHAI, POLACHECK,ITZHACK, NAIM,MICHAEL, EVRON,RUTH,DR, ZEHAVI,URI
Format:	Patent
Sprache:	ger
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY DERIVATIVES THEREOF HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SUGARS
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Beschreibung
Zusammenfassung:	Medicagenic acid and derivatives thereof of the general formula wherein R1 is H or acetyl; R2 is H, acetyl, beta -glucopyranosyl or alpha -glucopyrano (1-4) beta -glucopyranosyl and R3 is H or C1-6 alkyl are useful antifungal agents in combination with suitable carriers or diluents. They are active against a wide variety of medically important fungi and can be administered parenteral, topical or by aerosol. The derivatives identified as G2 and F are novel compounds, viz. medicagenic acid 3-o- beta -D-glucopyranoside and medicagenic acid 3-o- beta -D-maltoside.