Substituted 1,4-dihydropyridine-3-carboxylic acid derivatives
Substituted 1,4-dihydropyridine-3-carboxylic acid derivatives of the general formula I in which Ar represents a cycle of the formula in which Y denotes oxygen (O), sulphur (S), vinylene (-CH=CH-), azomethine (-CH=N-) or a group of the formula R1, R2 and R3 are identical or different and denote hydro...
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Sprache: | eng ; ger |
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Zusammenfassung: | Substituted 1,4-dihydropyridine-3-carboxylic acid derivatives of the general formula I in which Ar represents a cycle of the formula in which Y denotes oxygen (O), sulphur (S), vinylene (-CH=CH-), azomethine (-CH=N-) or a group of the formula R1, R2 and R3 are identical or different and denote hydrogen, C1-C6-alkyl, C3-C7-alkoxyalkyl, aryl, aryl-C1-C6-alkyl or aryloxy-C1-C6-alkyl, R4 and R5 are identical or different and denote hydrogen, hydroxyl, halogen, nitro, cyano, trifluoromethyl, C1-C4-alkyl, C1-C4-alkoxy, completely or partially fluorine-substituted C1-C4-alkoxy, C1-C4alkoxy-carbonyl, C2-C5-acyl, amino or mono- or di-C1-C4-alkylamino, R6, R7, R8 and R9 are identical or different and denote hydrogen, hydroxyl, halogen, C1-C4-alkyl, C1-C4-alkoxy, amino, mono- or di-C1-C4-alkylamino or completely or partially fluorine-substituted C1-C4-alkoxy, A denotes straight-chain or branched C2-C5-alkylene which can be substituted by C1-C4-alkoxy or aryl, and their salts are novel compounds for the treatment and prophylaxis of circulation-related diseases. |
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