DIHYDROPYRIDIN KOMBINATIONSPRAEPARAT

DIHYDROPYRIDIN KOMBINATIONSPRAEPARAT

A solid medicament formulation which can be administered orally, comprising 1 to 40 mg of a dihydropyridine of the formula in which R1 and R3 are always different from one another and represent alkyl which has 1 to 12 carbon atoms and which is optionally substituted once or several times by fluorine...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: GROSS,RAINER,DR, SCHRAMM,MATTHIAS,DR
Format: Patent
Sprache:ger
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:A solid medicament formulation which can be administered orally, comprising 1 to 40 mg of a dihydropyridine of the formula in which R1 and R3 are always different from one another and represent alkyl which has 1 to 12 carbon atoms and which is optionally substituted once or several times by fluorine or chlorine or which is optionally interrupted by an oxygen atom in the chain, and A represents the radical R2 representing one or two substituents from the group consisting of nitro, chlorine and trifluoromethyl, or represents and 0.1 to 100 mg of a cardioactive nitrate. The composition is cardio-active and the patient's tendency toward nitrate tolerance is reduced.