Novel heteroaromatic amine derivatives, pharmaceuticals comprising these compounds, and their preparation

The present invention relates to novel heteroaromatic amine derivatives of the general formula in which A is a -CH2-CH2-, -CH=CH- or -CH2-CO- group and B is a methylene, carbonyl or thiocarbonyl group, or A is a -CO-CO- or and B a methylene group, E is a straight-chain alkylene group which is optionally substituted by an alkyl group, G is a straight-chain alkylene group which is optionally substituted by an alkyl group, R1 is a hydrogen, chlorine or bromine atom, a trifluoromethyl, nitro, amino, alkylamino, dialkylamino, alkyl, hydroxyl, alkoxy or phenylalkoxy group, R2 is a hydrogen, chlorine or bromine atom, a hydroxyl, alkoxy, phenylalkoxy or alkyl group, or R1 and R2 together are an alkylenedioxy group, R3 is a hydrogen atom, an alkenyl, alkyl or phenylalkyl group and Het is a 5- or 6-membered heteroaromatic ring which contains one oxygen, sulphur or nitrogen atom, two nitrogen atoms or one nitrogen atom and one oxygen or sulphur atom and which is bonded via a carbon or nitrogen atom and to which additionally a phenyl ring can be fused, or an imidazo[1,2-a]pyridyl group in which the carbon skeleton of the abovementioned heteroaromatic radicals is [lacuna] by a halogen atom, an alkyl, hydroxyl, alkoxy, phenylalkoxy, phenyl, dimethoxyphenyl, nitro, amino, acetylamino, carbamoylamino, N-alkyl-carbamoylamino, ... Original abstract incomplete.