NEUE AROMATISCHE VERBINDUNGEN, IHRE HERSTELLUNG UND VERWENDUNG

Compounds of Formula (I) S-(CH2)n-A (I) in which S is a 17-spartein nucleus n is 0 or 1 and A is 2-furyl, 2-thienyl or 2-(N-alkyl)pyrryl when n=0, or 3-furyl or 3-thienyl when n=1, or pyridyl or a phenyl group of Formula (II) (II) in which at least one of R1, R2 and R3 is a defined substituent other...

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Hauptverfasser: BUSCHMANN,GERD,DR, SCHOEN,UWE,.DR, KUEHL,ULRICH,DR, KEHRBACH,WOLFGANG,.DR, HACHMEISTER,BERND,.DR
Format: Patent
Sprache:ger
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Zusammenfassung:Compounds of Formula (I) S-(CH2)n-A (I) in which S is a 17-spartein nucleus n is 0 or 1 and A is 2-furyl, 2-thienyl or 2-(N-alkyl)pyrryl when n=0, or 3-furyl or 3-thienyl when n=1, or pyridyl or a phenyl group of Formula (II) (II) in which at least one of R1, R2 and R3 is a defined substituent other than hydrogen. Such compounds and corresponding compounds in which A is an unsubstituted phenyl group are useful in pharmaceutical compositions as heart affecting agents. Methods of preparing such compounds and pharmaceutical compositions are also disclosed.