BIOSYNTHETISCHE 2,5-DIKETOGLUKONSAEURE-REDUKTASE, VERFAHREN, REKOMBINANTE ZELLEN UND EXPRESSIONSVEKTOREN ZU DEREN HERSTELLUNG UND IHRE VERWENDUNG ZUR HERSTELLUNG VON 2-KETO-L-GULONSAEURE

A protein having 2,5-diketogluconic acid (2,5-DKG) reductase activity is produced by recombinant host cells. This can be used to convert 2,5-DKG stereoselectively into 2-keto-L-gluonic acid (2-KLG) which is a useful intermediate in the production of ascorbic acid (vitamin C).

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Bibliographische Detailangaben
Hauptverfasser:	LIGHT, DAVID RICHARD, SAN FRANCISCO CALIFORNIA 94114, US, LAZARUS, ROBERT ALAN, SAN MATEO CALIFORNIA 94403, US, MILLER, JEFFREY VEACH, BELMONT CALIFORNIA 94002, US, ESTELL, DAVID AARON, MOUNTAIN VIEW CALIFORNIA 94043, US, RASTETTER, WILLIAM HARRY, SAN MATEO CALIFORNIA 94401, US
Format:	Patent
Sprache:	ger
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES USING MICROORGANISMS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	A protein having 2,5-diketogluconic acid (2,5-DKG) reductase activity is produced by recombinant host cells. This can be used to convert 2,5-DKG stereoselectively into 2-keto-L-gluonic acid (2-KLG) which is a useful intermediate in the production of ascorbic acid (vitamin C).