NEUE SUBSTITUIERTE ISOCHROMANE UND OXEPINE, DEREN SAEUREADDITIONSSALZE, DIESE ENTHALTENDE ARZNEIMITTEL UND VERFAHREN ZU DEREN HERSTELLUNG

NEUE SUBSTITUIERTE ISOCHROMANE UND OXEPINE, DEREN SAEUREADDITIONSSALZE, DIESE ENTHALTENDE ARZNEIMITTEL UND VERFAHREN ZU DEREN HERSTELLUNG

Isochromans and oxepines of the formula (I) in which R denotes a hydrogen atom or a straight or branched alkyl group having up to 4 C atoms, R denotes a hydrogen atom or a straight or branched alkyl group having up to 4 C atoms or, together with R , denotes an alkylene group having 3 to 5 C atoms, R...

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Hauptverfasser: ABELE,WOLFGANG,.DR, ESSER,FRANZ,.DR, REICHL,RICHARD,DR, TRAUNECKER,WERNER,DR, STRELLER,ILSE,DR, KOEPPE,HERBERT,.DR, GAIDA,WOLFRAM,DR, HOEFKE,WOLFGANG,DR
Format: Patent
Sprache:ger
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CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:Isochromans and oxepines of the formula (I) in which R denotes a hydrogen atom or a straight or branched alkyl group having up to 4 C atoms, R denotes a hydrogen atom or a straight or branched alkyl group having up to 4 C atoms or, together with R , denotes an alkylene group having 3 to 5 C atoms, R denotes a hydrogen atom or a straight or branched alkyl group having up to 4 C atoms, R denotes a hydrogen atom or a straight or branched alkyl group having up to 4 C atoms, R denotes a hydrogen atom or a straight or branched alkyl group having 1 to 6 C atoms or a pyridinyl group, R denotes a hydrogen atom, a fluorine, chlorine or bromine atom, a straight or branched alkyl group having 1 to 6 C atoms, a hydroxyl or alkoxy group having 1 to 4 C atoms or a trifluoromethyl group, R denotes a hydrogen atom, a fluorine, chlorine or bromine atom, a straight or branched alkyl group having 1 to 6 C atoms, a hydroxyl or alkoxy group having 1 to 4 C atoms or, together with R , denotes a methylenedioxy group, R denotes a hydrogen atom, or a hydroxyl or alkoxy group having 1 to 4 C atoms, m denotes the numbers 1 or 2 and n denotes the numbers 1, 2 or 3, and their acid addition salts. The compounds have calcium antagonist and antihypertensive activity.