NEUE 11-PIPERAZINYL-5H-IMIDAZO(2,1-C)(1,4)BENZODIAZEPINE, VERFAHREN ZU IHRER HERSTELLUNG UND ZWISCHENPRODUKTE UND ERSTERE ENTHALTENDE ARZNEIMITTEL

Compounds of the formula wherein R1 and R2, which may be identical to or different from each other, are each hydrogen, fluorine, chlorine, bromine, trifluoromethyl, hydroxyl, nitro, amino, cyano, methylsulfonamido, alkyl of 1 to 4 carbon atoms, alkoxy of 1 to 3 carbon atoms, (alkyl of 1 to 3 carbon...

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Hauptverfasser: FUEGNER,ARMIN,DR, WALTHER,GERHARD,DR, SCHNEIDER,CLAUS,DR, WEBER,KARL-HEINZ,DR
Format: Patent
Sprache:ger
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Zusammenfassung:Compounds of the formula wherein R1 and R2, which may be identical to or different from each other, are each hydrogen, fluorine, chlorine, bromine, trifluoromethyl, hydroxyl, nitro, amino, cyano, methylsulfonamido, alkyl of 1 to 4 carbon atoms, alkoxy of 1 to 3 carbon atoms, (alkyl of 1 to 3 carbon atoms)thio or (alkanoyl of 2 to 4 carbon atoms)amino; R3 is hydrogen, fluorine, chlorine, bromine or alkyl of 1 to 3 carbon atoms; R4 is hydrogen, alkyl of 1 to 4 carbon atoms, hydroxy(alkyl of 2 to 4 carbon atoms), (alkoxy of 1 to 2 carbon atoms)-(alkyl of 2 to 4 carbon atoms), alkenyl of 3 to 6 carbon atoms, alkynyl of 3 to 6 carbon atoms, cycloalkyl of 3 to 7 carbon atoms, (cycloalkyl of 3 to 7 carbon atoms)-(alkyl of 1 to 3 carbon atoms) or (unsubstituted or substituted phenyl)-(alkyl of 1 to 3 carbon atoms) where the substituent is fluorine, chlorine, bromine, methyl, methoxy, hydroxyl or trifluoromethyl; and n is 1 or 2; and non-toxic, pharmacologically acceptable acid addition salts thereof. The compounds as well as their salts are useful as antiallergic.