VERFAHREN ZUR HERSTELLUNG VON CEPHEMVERBINDUNGEN

VERFAHREN ZUR HERSTELLUNG VON CEPHEMVERBINDUNGEN

Process for the preparation of cephem compounds of the formula wherein R is optionally substituted aminothiazolyl or amino-1,2,4-thiadiazolyl, A is optionally substituted pyridinium, R1 is hydrogen or methoxy and R2 are special aliphatic substituents, by a nucleophilic replacement in the substituent...

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Hauptverfasser: LATTRELL,RUDOLF,DR, SCHWAB,WILFRIED,DR, KIRRSTETTER,REINER,DR, DUERCKHEIMER,WALTER,DR
Format: Patent
Sprache:ger
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Zusammenfassung:Process for the preparation of cephem compounds of the formula wherein R is optionally substituted aminothiazolyl or amino-1,2,4-thiadiazolyl, A is optionally substituted pyridinium, R1 is hydrogen or methoxy and R2 are special aliphatic substituents, by a nucleophilic replacement in the substituent in 3-position in the presence of tri-C1C4-alkyl iodosilane.