CHROMON- UND THIOCHROMONSUBSTITUIERTE 1,4-DIHYDROPYRIDINDERIVATE, MEHRERE VERFAHREN ZU IHRER HERSTELLUNG SOWIE IHRE VERWENDUNG IN ARZNEIMITTELN

CHROMON- UND THIOCHROMONSUBSTITUIERTE 1,4-DIHYDROPYRIDINDERIVATE, MEHRERE VERFAHREN ZU IHRER HERSTELLUNG SOWIE IHRE VERWENDUNG IN ARZNEIMITTELN

Dihydropyridines of the formula in which R1, R2, R5, R6, R7 and R8 can be hydrogen or various halogen or organic radicals, R4 is an optionally substituted hydrocarbon radical, A is a direct bond, an alkylene chain with 1 to 20 C atoms or an alkenylene chain with 2 to 20 atoms, the chains being optio...

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Hauptverfasser: FRANCKOWIAK,GERHARD,.DR, THOMAS,GUENTER,DR, GROSS,RAINER,DR, SCHRAMM,MATTHIAS,DR, GOLDMANN,SIEGFRIED,.DR
Format: Patent
Sprache:ger
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:Dihydropyridines of the formula in which R1, R2, R5, R6, R7 and R8 can be hydrogen or various halogen or organic radicals, R4 is an optionally substituted hydrocarbon radical, A is a direct bond, an alkylene chain with 1 to 20 C atoms or an alkenylene chain with 2 to 20 atoms, the chains being optionally interrupted by O or S, X is O or S and Y is a direct bond, O, S, -NH- or -N- alkyl with 1 to 8 C atoms, or a pharmaceutically acceptable salt thereof, are useful as cardiotonic agents for improving heart contractility, antihypotonic agents, for lowering the blood sugar level, for detumescing mucous membranes and for influencing the salt and liquid balance.